Aspirin rarely used for colorectal cancer prevention

People with Lynch syndrome have a significantly increased risk of developing colorectal cancer and other types of cancer due to a hereditary predisposition. The CAPP2 study had already shown in this high-risk group that acetylsalicylic acid can significantly reduce the long-term risk of colorectal cancer. The study examined a comparatively high daily dose of 600 milligrams. The recently published international CaPP3 study now suggests that even a lower dose of 100 milligrams daily could have a similar cancer-preventive effect while causing fewer side effects, particularly bleeding complications. The research is published in The Lancet Gastroenterology & Hepatology journal.